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Clinical Molecular Technologist III

Medical College of Wisconsin

Last Updated: 5/29/22

Job Description

With minimal oversight from the Manager/Supervisor of the Precision Medicine Laboratory, the Molecular Technologist will be responsible for processing both clinical and research samples using cutting-edge technologies for nucleic acid analysis, including but not limited to next-generation sequencing, Sanger sequencing, ddPCR and associated sample preparation technologies. These activities will be performed under CLIA/CAP regulations and will directly impact human health and thus must meet the highest possible standards for quality and integrity. The Technologist I, II, or III are distinguishable primarily by level of experience, supervision required, proficiency in problem solving, certification and wider range of training.

Primary Functions

This role is responsible for the efficient and quality execution of sample accessioning, processing and data generation for the Precision Medicine Laboratory. This includes working with the manager to maintain all documentation required for operation under CLIA/CAP certification, including review and writing of SOPs as necessary and use of sample tracking systems in accordance with standard operating procedures.

  • Timely completion of training assigned by management or laboratory director to meet the needs of laboratory operations
  • Ensure sample accessioning is performed in an accurate manner to enable effective testing of samples downstream as ordered.
  • Work with pathologist to evaluated neoplastic content of sample as needed
  • Sample processing including nucleic acid purification and preparation for sequencing and PCR is performed per established processes
  • Accurate and timely maintenance of operational metrics
  • Maintains and updates associated process documentation, participates in continuous process improvements and ongoing training
  • Performs quality control of samples processed and data generated prior to sending to next steps.
  • Maintenance of auxiliary and capital equipment and instrumentation

This role is also responsible for the development and validation of new methodologies, including establishing novel workflows, evaluating new instrumentation and protocols as deemed necessary by the clinical laboratory manager and/or director

  • Makes technological/scientific contributions to development projects
  • Research, evaluate, and implement new and emerging applications and tools to improve current clinical offerings and to support new clinical offerings. This will involve working closely and coordinating with regulatory, computational sciences, IT, and management groups in accordance with established professional development goals

Preferred Schedule:

Position Requirements:

Knowledge – Skills – Abilities
Well organized, with strong attention to detail and process is required. Ability to learn new tasks and procedures in appropriate timeframes. Experience in data management, including laboratory information management systems. Excellent written and verbal skills as would be required to communicate scientific details and respond to custom inquiries.


Minimum Required Education: Bachelor’s degree

Minimum Required Experience: 5 years experience (OR 3 years experience and a Masters Degree)

Preferred Experience: 3 years in product/clinical/research assay development

Field: Molecular Biology

Certification: ASCP Certified Technologist in Molecular Biology (MB) required

About MCW
The Medical College of Wisconsin (MCW) is one of the largest healthcare employers in Wisconsin. We are a distinguished leader and innovator in the education and development of the next generation of physicians, scientists, pharmacists and health professionals; we discover and translate new knowledge in the biomedical and health sciences; we provide cutting-edge, collaborative patient care of the highest quality; and we improve the health of the communities we serve.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

Company Details

Milwaukee, Wisconsin, United States